Chinese invented bristled toothbrushes made of bone or bamboo handles and hog bristles in 1498.

Additional Information:

• Who invented the toothbrush? | Science Illustrated
  The first bristle toothbrush was invented in China in 1498, where coarse boar hairs were attached to handles made of bamboo or bone. Boar bristles were used until 1938, when nylon bristles were introduced by the company Dupont de Nemours.Apr 26, 2012
• Who invented the toothbrush and when was it? (Everyday Mysteries …
  The bristle toothbrush, similar to the type used today, was not invented until 1498 in China. The bristles were actually the stiff, coarse hairs taken from the back of …
• Toothbrush – Wikipedia
  Jump to History – Before the invention of the toothbrush, a variety of oral hygiene … The first bristle toothbrush resembling the modern one was found in …
• History of Toothpaste – Toothbrush History – Colgate
  The Chinese are believed to have invented the first natural bristle toothbrush made from the bristles from pigs’ necks in the 15th century, with the bristles …
• A Visual History of the Toothbrush | Museum of Every Day Life
  The first bristle toothbrush was invented by the Chinese during the Tang Dynasty (619-907) and was most likely made from the coarse hairs of the cold-climate …