American researcher Kary B. Mullis, a staff chemist for the Cetus Corporation in Emeryville, CA, USA invented DNA chain polymerization in 1983. The DNA polymerase chain reaction allowed Mullis to replicate an entire chain of deoxyribonucleic acid (DNA) required from a single DNA strand. The technique allowed for genetic engineering, human genome mapping, DNA fingerprinting, evolutionary science, and genetic diagnosis. Mullis won the 1993 Nobel Prize in Chemistry for his work.
Kary B. Mullis
Emeryville, CA, USA
- Polymerization of Nucleotides
Polymerization of Nucleotides (Phosphodiester Bonds) Nucleotides are joined together similarly to other biological molecules, by a condensation reaction that releases a small, stable molecule. … The 5′ group of a nucleotide triphosphate is held close to the free 3′ hydroxyl group of a nucleotide chain.
- DNA Is Replicated by Polymerases that Take Instructions from …
Polymerization Reaction Catalyzed by DNA Polymerases. The chain-elongation reaction catalyzed by DNA polymerases is a nucleophilic attack by the 3′- …
- Molecular mechanism of DNA replication (article) | Khan …
DNA replication requires other enzymes in addition to DNA polymerase, … 3′ end as a “hook,” adding a nucleotide to this group in the polymerization reaction.
- Polymers: from DNA to rubber ducks – Curious
Jan 30, 2017 – One way of thinking about polymers is like a chain of connected-up paperclips. paperclip patterns and polymers. A polymer is a large molecule …
- Sequence-controlled polymer – Wikipedia
DNA, RNA and proteins are most common sequence-controlled polymers in living creatures. Inspired by them, polymerization methods, utilizing DNA or RNA as …